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Research Articles

Group’s Publications in peer-reviewed scientific journals:

Design, synthesis and pharmacological evaluation of a tripeptide targeting the extracellular N-domain of CRF1 receptor

Τ. Mavromoustakos, V.Karageorgos, J.Andreadelis, E.Dermitzaki, G. Kordopati, E. Stylos, K.Spyridaki, S. Sakellaris, M.Vanioti, G. Leonis, K.D. Marousis, A. Kostagianni, G. Kokotos, M. Venihaki, A. Spyroulias, T. Tselios, A. Tzakos, A. Margioris, G. Liapakis. Design, synthesis and pharmacological evaluation of a tripeptide targeting the extracellular N-domain of CRF1 receptor. Amino Acids revision pending

Unsaturated fatty acid-induced conformational transitions and aggregation of the repeat domain of Tau. Molecules 25, Ε2716, (2020)

C.G. Barracchia, R. Tira, F. Parolini, F. Munari, L. Bubacco, G.A. Spyroulias, M. D’Onofrio, M. Assfalg. Unsaturated fatty acid-induced conformational transitions and aggregation of the repeat domain of Tau. Molecules 25, Ε2716, (2020).

Marine-Derived Surface Active Agents: Health-Promoting Properties and Blue Biotechnology-Based Applications

Ι. Anestopoulos, D.-E. Kiousi, A. Klavaris, M. Maijo, A. Serpico, A. Suarez, G. Sanchez, K. Salek, S. A. Chasapi, A. A. Zompra, A. Galanis, G. A. Spyroulias, S. R. Euston, L. Gombau, A. Pappa, M. I. Panayiotidis. Marine-Derived Surface Active Agents: Health-Promoting Properties and Blue Biotechnology-Based Applications. Biomolecules 10, Ε885, (2020).

Metabolic changes in early neonatal life: NMR analysis of the neonatal metabolic profile to monitor postnatal metabolic adaptations

Ι. Georgakopoulou, S.A. Chasapi, S.E. Bariamis, A. Varvarigou, M. Spraul, G.A. Spyroulias. Metabolic changes in early neonatal life: NMR analysis of the neonatal metabolic profile to monitor postnatal metabolic adaptations. Metabolomics 16, 58 (2020).

1H, 13C and 15N Backbone and side-chain resonance assignment of UbcH7 E2 Ubiquitin Conjugating Enzyme

Κ. Marousis, M. Birkou, A. Asimakopoulou, G.A. Spyroulias. 1H, 13C and 15N Backbone and side-chain resonance assignment of UbcH7 E2 Ubiquitin Conjugating Enzyme. Biomol. NMR Assign. 14, 73-78, (2020).

Deciphering the nucleotide and RNA binding selectivity of the Mayaro virus macro domain

Α.C. Tsika, S. Melekis, S.-A. Tsatsouli, N. Papageorgiou, M.J. Maté, B. Canard, B. Coutard, D. Bentrop, G.A. Spyroulias. Deciphering the nucleotide and RNA binding selectivity of the Mayaro virus macro domain. JMB 431, 2282-2296, (2019).

Conformational plasticity of the VEEV macro domain is important for binding of ADP-ribose

G.I. Makrynitsa, D. Ntonti, K.D. Marousis, M. Birkou, M.-T. Matsoukas, S. Asami, D. Bentrop, N. Papageorgiou, B. Canard, B. Coutard, G.A. Spyroulias. Conformational plasticity of the VEEV macro domain is important for binding of ADP-ribose. J. Struct. Biol.  206, 119-127, (2019).

Biosynthesis of rhamnolipid by a Marinobacter species expands the paradigm of biosurfactant synthesis to a new genus of the marine microflora

L. Tripathi, M. Twigg, A. Zompra, K. Salek, V.U. Irorere, T. Gutierrez, G.A. Spyroulias, R. Marchant, I.M. Banat. Biosynthesis of rhamnolipid by a Marinobacter species expands the paradigm of biosurfactant synthesis to a new genus of the marine microflora. Microbial Cell Factories 18, 164, (2019).

Novel stable analogues of the Neurotensin C-terminal hexapeptide containing unnatural amino acids

V. Magafa, M.-T. Matsoukas, V. Karageorgos, E. Dermitzaki, R. Exarchakou, E.K. Stylos, M. Pardalos, A.N. Margioris, G. Varvounis, A.G. Tzakos,G.A. Spyroulias, G. Liapakis. Novel stable analogues of the Neurotensin C-terminal hexapeptide containing unnatural amino acids. Amino Acids 51, 1009-1022, (2019).

Therapeutic Targeting of the Soluble Guanylate Cyclase

G. Makrynitsa, A. Argyriou, A. Zompra, G.A.Spyroulias, S. Topouzis. Therapeutic Targeting of the Soluble Guanylate Cyclase.Curr. Med. Chem. 26, 2730-2747, (2019).